• Linkage and Association Analysis
  • The pattern discovery-based method for multi-locus association analysis
  • The Transmission Disequilibrium Test (TDT)
  • The Haplotype-based haplotype relative Risk Test (HHRR)
  • LOD Analysis


• Micro-array Gene Expression Data Analysis
  • Expression signature analysis
  • Gene Ontology and pathway analysis
  • Bio-rationale collation for potential targets


• Integrated pharmacogenomic/pharmacogenetic biomarker identification
  • Identify genotype-expression correlation
  • Identify haplotype-expression correlation
  • Identify population-specific classifiers for expression level prediction

Given the expanding needs in biomedical research for advances in a variety of areas of information science and technology, we focus mainly on developing generalizable, scalable, extensible, interoperable, and user-friendly computational tools and resources. Currently we are developing software solutions in the following areas:

• Tools for data acquisition, archiving, querying, retrieval, visualization, integration, and management
• Platform-independent translational tools for data exchange and for  promoting interoperability 
• Web-based linkage tools for data sharing and tools for electronic communication